700015 | 7-ketocholesterol
3ß-hydroxy-5-cholestene-7-one

7-ketocholesterol
3ß-hydroxy-5-cholestene-7-one
CAS Registry Number is a Registered Trademark of the American Chemical Society
7-oxo-5-cholesten-3ß-ol-7-one
5-cholesten-3ß-ol-7-one
3ß-hydroxycholest-5-en-7-one
110806
- ChemDraw File
- 3D Structure
- Structure
- Safety Data Sheet
- Certificate of Analysis (Lot No. 700015P-100MG-A-017 and 5102PLA017)
- Certificate of Analysis (Lot No. 700015P-50MG-A-016 and 5102PKA016)
- Certificate of Analysis (Lot No. 700015P-5MG-A-016 and 5102PHA016)
- Certificate of Analysis (Lot No. 700015P-50MG-A-017 and 5102PKA017)
- Certificate of Analysis (Lot No. 700015P-5MG-A-017 and 5102PHA017)
- Certificate of Analysis (Lot No. 700015P-100MG-B-017 and 5102PLB017)
- Certificate of Analysis (Lot No. 700015P-5MG-B-017 and 5102PHB017)
- Certificate of Analysis (Lot No. 700015P-5MG-C-017 and 5102PHC017)
- Certificate of Analysis (Lot No. 700015P-50MG-B-017 and 5102PKB017)
- Certificate of Analysis (Lot No. 700015P-100MG-C-017 and 5102PLC017)
- Certificate of Analysis (Lot No. 700015P-5MG-D-017 and 5102PHD017)
- Certificate of Analysis (Lot No. 700015P-100MG-D-017 and 5102PLD017)
- Certificate of Analysis (Lot No. 700015P-5MG-E-017 and 5102PHE017)
- Certificate of Analysis (Lot No. 700015P-100MG-E-017 and 5102PLE017)
- Certificate of Analysis (Lot No. 700015P-50MG-C-017 and 5102PKC017)
- Certificate of Analysis (Lot No. 700015P-5MG-F-017 and 5102PHF017)
- Certificate of Analysis (Lot No. 700015P-50MG-D-017 and 5102PKD017)
- Certificate of Analysis (Lot No. 700015P-50MG-E-017 and 5102PKE017)
- Certificate of Analysis (Lot No. 700015P-100MG-F-017 and 5102PLF017)
- Certificate of Analysis (Lot No. 700015P-5MG-G-017 and 5102PHG017)
- Certificate of Analysis (Lot No. 700015P-50MG-A-018 and 5102PKA018)
- Certificate of Analysis (Lot No. 700015P-5MG-B-018 and 5102PHB018)
Hutchinson SA, Lianto P, Roberg-Larsen H, Battaglia S, Hughes TA, Thorne JL. ER-Negative Breast Cancer Is Highly Responsive to Cholesterol Metabolite Signalling. Nutrients. 2019 Nov 1;11(11). pii: E2618. doi: 10.3390/nu11112618.
PubMed ID: 31683867Rudd-Schmidt JA, Hodel AW, Noori T, Lopez JA, Cho HJ, Verschoor S, Ciccone A, Trapani JA, Hoogenboom BW, Voskoboinik I. Lipid order and charge protect killer T cells from accidental death. Nat Commun. 2019 Nov 27;10(1):5396. doi: 10.1038/s41467-019-13385-x.
PubMed ID: 31776337Rossin D, Barbosa-Pereira L, Iaia N, Testa G, Sottero B, Poli G, Zeppa G, Biasi F. A Dietary Mixture of Oxysterols Induces In Vitro Intestinal Inflammation through TLR2/4 Activation: The Protective Effect of Cocoa Bean Shells. Antioxidants (Basel). 2019 May 31;8(6). pii: E151. doi: 10.3390/antiox8060151.
PubMed ID: 31151323Fidalgo Rodríguez JL, Dynarowicz-Latka P, Minones Conde J. Interactions of cholesterol and 7‑ketocholesterol with unsaturated fatty acids of different unsaturation degree - The monolayer study. Biochim Biophys Acta Biomembr. 2019 Aug 1;1861(8):1428-1436. doi: 10.1016/j.bbamem.2019.06.002. Epub 2019 Jun 9.
PubMed ID: 31189076Tajima N, Xiaoyan L, Taniguchi M, Kato N. 24S-hydroxycholesterol alters activity of large-conductance Ca2+-dependent K+ (slo1 BK) channel through intercalation into plasma membrane. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 May 25. pii: S1388-1981(19)30085-X. doi: 10.1016/j.bbalip.2019.05.010. [Epub ahead of print]
PubMed ID: 31136842Rossin D, Dias IHK, Solej M, Milic I, Pitt AR, Iaia N, Scoppapietra L, Devitt A, Nano M, Degiuli M, Volante M, Caccia C, Leoni V, Griffiths HR, Spickett CM, Poli G, Biasi F. Increased production of 27-hydroxycholesterol in human colorectal cancer advanced stage: Possible contribution to cancer cell survival and infiltration. Free Radic Biol Med. 2019 Mar 23;136:35-44. doi: 10.1016/j.freeradbiomed.2019.03.020. [Epub ahead of print]
PubMed ID: 30910555Fidalgo Rodríguez JL, Dynarowicz-Latka P, Miñones Conde J. Effects of saturated and polyunsaturated fatty acids on interactions with cholesterol versus 7-ketocholesterol in Langmuir monolayers and their potential biological implications. Colloids Surf B Biointerfaces. 2019 Feb 1;174:189-198. doi: 10.1016/j.colsurfb.2018.08.052. Epub 2018 Aug 25.
PubMed ID: 30463048Wang X, Sun J, Zhao XE, Xu Y, Sun L, Zhu S, You J, Wang X. Stable isotope labeling derivatization coupled with magnetic dispersive solid phase extraction for the determination of hydroxyl-containing cholesterol and metabolites by in vivo microdialysis and ultra-high performance liquid chromatography tandem mass spectrometry. J Chromatogr A. 2019 Feb 14. pii: S0021-9673(19)30151-7. doi: 10.1016/j.chroma.2019.02.021. [Epub ahead of print]
PubMed ID: 30797576