699810 | PHAD®-504
Monophosphoryl Lipid A-504
PHAD®-504
Monophosphoryl Lipid A-504
PHAD®-504 was designed as a synthetic structural analog of detoxified MPLA derived from E. coli lipopolysaccharide (LPS). It is structurally similar to PHAD®, differing only in the length of a single fatty acid chain. As expected, the activity of PHAD®-504 is quite similar to that of PHAD®, making the two products interchangeable as adjuvants in vaccine or immunotherapy formulations.
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C94H180 N3O22P
Percent Composition
C 65.06% H 10.45% N 2.42% O 20.28% P 1.78 %
Purity
>99%
Stability
1 year
Storage Temperature
-20°C
Formula Weight
1735.420
Exact Mass
1734.280
- ChemDraw File
- 3D Structure
- Structure
- Brochure
- Safety Data Sheet
- Certificate of Analysis (Lot No. 699810P-1MG-A-010 and 5087PGA010)
- Certificate of Analysis (Lot No. 699810P-5MG-A-010 and 5087PHA010)
- Certificate of Analysis (Lot No. 699810P-1MG-B-010 and 5087PGB010)
- Certificate of Analysis (Lot No. 699810P-5MG-B-010 and 5087PHB010)
- Certificate of Analysis (Lot No. 699810P-5MG-C-010 and 5087PHC010)
- Certificate of Analysis (Lot No. 699810P-1MG-C-010 and 5087PGC010)
- Certificate of Analysis (Lot No. 699810P-5MG-D-010 and 5087PHD010)
Ji Y, An J, Hwang D, Ha DH, Lim SM, Lee C, Zhao J, Song HK, Yang EG, Zhou P, Chung HS. Metabolic engineering of Escherichia coli to produce a monophosphoryl lipid A adjuvant. Metab Eng. 2020 Jan;57:193-202. doi: 10.1016/j.ymben.2019.11.009. Epub 2019 Nov 28. PMID: 31786244; PMCID: PMC6960009.
PubMed ID: 31786244