699810 | PHAD®-504

Monophosphoryl Lipid A-504

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Size SKU Packaging Price
5mg 699810P-5mg 699810P-5mg $839.50
1mg 699810P-1mg 699810P-1mg $209.87
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PHAD®-504

PHAD®-504

Monophosphoryl Lipid A-504

PHAD®-504 was designed as a synthetic structural analog of detoxified MPLA derived from E. coli lipopolysaccharide (LPS). It is structurally similar to PHAD®, differing only in the length of a single fatty acid chain. As expected, the activity of PHAD®-504 is quite similar to that of PHAD®, making the two products interchangeable as adjuvants in vaccine or immunotherapy formulations. 

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C94H180 N3O22P
Percent Composition
C 65.06% H 10.45% N 2.42% O 20.28% P 1.78 %
Purity
>99%
Stability
1 year
Storage Temperature
-20°C
Formula Weight
1735.420
Exact Mass
1734.280

Ji Y, An J, Hwang D, Ha DH, Lim SM, Lee C, Zhao J, Song HK, Yang EG, Zhou P, Chung HS. Metabolic engineering of Escherichia coli to produce a monophosphoryl lipid A adjuvant. Metab Eng. 2020 Jan;57:193-202. doi: 10.1016/j.ymben.2019.11.009. Epub 2019 Nov 28. PMID: 31786244; PMCID: PMC6960009.

 PubMed ID: 31786244