siRNA Delivery System | 640009

Delivery System for siRNA/DNA



All Prices in US Dollars
Custom packaging is calculated at $4.00 per aliquot and will be charged at the time of shipping.

Custom Packaging: Before clicking add to cart, from the drop down arrow select custom packaging. Next, edit the quantities (and concentration for solutions) information. Finally, click add to cart.

  • Product
  • Data
  • Downloads
  • Reference
The self-assembly of custom-synthesized MVL5 and GMO with siRNA results in the formation of a double-gyroid bicontinuous inverted cubic phase with colocalized lipid/siRNA domains. The high charge density (due to MVL5) and positive Gaussian modulus of the GMO-containing membranes confer optimal electrostatic and elastic properties for endosomal escape, enabling efficient siRNA delivery and effective, specific gene silencing.
Leal, C., K.K. Ewert, R.S. Shirazi, N.F. Bouxsein, and C.R. Safinya. (2011). Nanogyroids incorporating multivalent lipids: enhanced membrane charge density and pore forming ability for gene silencing. Langmuir 27:7691-7. [PubMed]