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siRNA Delivery Kit | 640009

Delivery System for siRNA/DNA

640009

640009-
1EA
$450.00

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The self-assembly of custom-synthesized MVL5 and GMO with siRNA results in the formation of a double-gyroid bicontinuous inverted cubic phase with colocalized lipid/siRNA domains. The high charge density (due to MVL5) and positive Gaussian modulus of the GMO-containing membranes confer optimal electrostatic and elastic properties for endosomal escape, enabling efficient siRNA delivery and effective, specific gene silencing.
Storage
-20°C
Leal, C., K.K. Ewert, R.S. Shirazi, N.F. Bouxsein, and C.R. Safinya. (2011). Nanogyroids incorporating multivalent lipids: enhanced membrane charge density and pore forming ability for gene silencing. Langmuir 27:7691-7. [PubMed]