640009 | siRNA Delivery Kit

Delivery System for siRNA/DNA


Size SKU Price
1EA 640009-1EA 640009-1EA $679.11


siRNA Delivery Kit

Delivery System for siRNA/DNA

The self-assembly of custom-synthesized MVL5 and GMO with siRNA results in the formation of a double-gyroid bicontinuous inverted cubic phase with colocalized lipid/siRNA domains. The high charge density (due to MVL5) and positive Gaussian modulus of the GMO-containing membranes confer optimal electrostatic and elastic properties for endosomal escape, enabling efficient siRNA delivery and effective, specific gene silencing.

Light Sensitive
Storage Temperature

Leal C, Ewert KK, Shirazi RS, Bouxsein NF, Safinya CR. Nanogyroids incorporating multivalent lipids: enhanced membrane charge density and pore forming ability for gene silencing. Langmuir. 2011 Jun 21;27(12):7691-7. doi: 10.1021/la200679x. Epub 2011 May 25. PMID: 21612245; PMCID: PMC3119580.

PubMed ID: 21612245
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