640009 | siRNA Delivery Kit

Delivery System for siRNA/DNA


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Size SKU Price
1EA 640009-1EA 640009-1EA $509.07
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siRNA Delivery Kit

Delivery System for siRNA/DNA

The self-assembly of custom-synthesized MVL5 and GMO with siRNA results in the formation of a double-gyroid bicontinuous inverted cubic phase with colocalized lipid/siRNA domains. The high charge density (due to MVL5) and positive Gaussian modulus of the GMO-containing membranes confer optimal electrostatic and elastic properties for endosomal escape, enabling efficient siRNA delivery and effective, specific gene silencing.

Hygroscopic
No
Light Sensitive
No
Storage Temperature
-20°C
Formula Weight
0.000
Exact Mass
0.000

Leal C, Ewert KK, Shirazi RS, Bouxsein NF, Safinya CR. Nanogyroids incorporating multivalent lipids: enhanced membrane charge density and pore forming ability for gene silencing. Langmuir. 2011 Jun 21;27(12):7691-7. doi: 10.1021/la200679x. Epub 2011 May 25. PMID: 21612245; PMCID: PMC3119580.

PubMed ID: 21612245