640009 | siRNA Delivery Kit
Delivery System for siRNA/DNA
Info
siRNA Delivery Kit
Delivery System for siRNA/DNA
The self-assembly of custom-synthesized MVL5 and GMO with siRNA results in the formation of a double-gyroid bicontinuous inverted cubic phase with colocalized lipid/siRNA domains. The high charge density (due to MVL5) and positive Gaussian modulus of the GMO-containing membranes confer optimal electrostatic and elastic properties for endosomal escape, enabling efficient siRNA delivery and effective, specific gene silencing.
Data
No
No
-20°C
References
Powered by BiozLeal C, Ewert KK, Shirazi RS, Bouxsein NF, Safinya CR. Nanogyroids incorporating multivalent lipids: enhanced membrane charge density and pore forming ability for gene silencing. Langmuir. 2011 Jun 21;27(12):7691-7. doi: 10.1021/la200679x. Epub 2011 May 25. PMID: 21612245; PMCID: PMC3119580.
PubMed ID: 21612245
Certificates of Analysis
- Certificate of Analysis (Lot No. 640009P-1EA-A-010 and 5081-AA010)
- Certificate of Analysis (Lot No. 640009P-1EA-A-010 and 5081PAA010)
- Certificate of Analysis (Lot No. 640009P-1EA-011 and 5081PAA011)
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