550001 | Aurora®-DSG

Aurora®-DSG Nanoparticles


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500µg 550001P-500ug 550001P-500ug $740.00
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Aurora®-DSG

Aurora®-DSG Nanoparticles

This new conjugate from Avanti consists of an Aurora™ gold cluster capped with triphenylphosphine ligands and a single diglyceride ligand. Fifty-five gold atom nanoparticles, first described by Schmid, are fascinating structures that are commonly used for contrast agents in various imaging applications. Ideally this particle, unlike larger colloidal style particles, is less intrusive to the target application and behaves like an organic entity instead of a foreign metallic probe. They also are a great generic platform for bottom up synthesis of novel, gold-centered nanostructures due to the ease and completeness of ligand exchange reactions. This complex is readily visible under TEM and can also be viewed in optical microscopes if further processed using a silver development procedure.

Hygroscopic
No
Light Sensitive
No
Molecular Formula
Au55C262H265P12NO7
Purity
>99%
Stability
1 Years
Storage Temperature
4°C
Formula Weight
14745.270
Exact Mass
0.000
Synonyms
Gold-Lipid Conjugate
1,2-distearoyl-sn-glycero-3-(Aurora Nanoparticle)

Sot J, Mendanha-Neto SA, Busto JV, García-Arribas AB, Li S, Burgess SW, Shaw WA, Gil-Carton D, Goñi FM, Alonso A. The interaction of lipid-liganded gold clusters (Aurora ™) with lipid bilayers. Chem Phys Lipids. 2019 Jan;218:40-46. doi: 10.1016/j.chemphyslip.2018.11.007. Epub 2018 Nov 28.

PubMed ID: 30502315

Sot J, Mendanha-Neto SA, Busto JV, García-Arribas AB, Li S, Burgess SW, Shaw WA, Gil-Carton D, Goñi FM, Alonso A. The interaction of lipid-liganded gold clusters (Aurora TM) with lipid bilayers. Chem Phys Lipids. 2018 Nov 28. pii: S0009-3084(18)30238-X. doi: 10.1016/j.chemphyslip.2018.11.007. [Epub ahead of print]

PubMed ID: 30502315

Miao Li, Theobald Lohmüller, and Jochen Feldmann (2014).Optical Injection of Gold Nanoparticles into Living Cells. Nano Lett., Article ASAP DOI: 10.1021/nl504497m Publication Date (Web): December 11, 2014.

PubMed ID: 25496343

Günter Schmid and Benedetto Corain. Nanoparticulated Gold: Syntheses, Structures, Electronics, and Reactivities. Eur. J. Inorg. Chem. 2003, 3081-3098.


Lewandowski, W., K. Jatczak, D. Pociecha, and J. Mieczkowski. (2013). Control of gold nanoparticle superlattice properties via mesogenic ligand architecture. Langmuir 29:3404-10.

PubMed ID: 23421504

Balasubramanian, R., R. Guo, A.J. Mills, and R.W. Murray. (2005). Reaction of Au(55)(PPh(3))(12)Cl(6) with thiols yields thiolate monolayer protected Au(75) clusters. J Am Chem Soc 127:8126-32.

PubMed ID: 15926840

Kojima, C., Y. Hirano, and K. Kono. (2009). Chapter 7 - Preparation of complexes of liposomes with gold nanoparticles. Methods Enzymol 464:131-45.

PubMed ID: 19903553

Murphy, C.J., A.M. Gole, J.W. Stone, P.N. Sisco, A.M. Alkilany, E.C. Goldsmith, and S.C. Baxter. (2008). Gold nanoparticles in biology: beyond toxicity to cellular imaging. Acc Chem Res 41:1721-30.

PubMed ID: 18712884

Marchesano, V., Y. Hernandez, W. Salvenmoser, A. Ambrosone, A. Tino, B. Hobmayer, J. M de la Fuente, and C. Tortiglione. (2013). Imaging inward and outward trafficking of gold nanoparticles in whole animals. ACS Nano 7:2431-42.

PubMed ID: 23448235

Au55-TG-7-5-2013.gif