300213 | LNP Lipid Blend 2
LNP Lipid Blend 2
LNP Lipid Blend 2
LNP Lipid Blend 2
This pre-mixed lipid blend is composed of components suitable for producing nucleic acid-based lipid nanoparticles. Recommended for use with DNA/plasmid cargo.
Instructions for using the LNP Lipid Blend 2:
1. Add 1-mL of ethanol to the vial. Mix well to achieve full dissolution.*
2. Dissolve your nucleic acid in buffer of choice.**
3. Use solvent injection to create LNPs. Different parameters and cargo will result in different particle size results.
4. Dialyze the final formulation against buffer of choice to remove residual ethanol.
Catalog Number | Component Name | Mole Fraction |
890890 | DOTAP | 49 |
700107 | Sitosterol (synthetic from plant sterol) | 38.5 |
850365 | DSPC | 11 |
880151 | DMG-PEG2000 | 1.5 |
*Note: low heat, sonication, or vortexing can be used as needed
**Note: common buffers include citrate, Tris, or PBS
Hygroscopic
No
Light Sensitive
No
Stability
3 Months
Storage Temperature
-20°C
Formula Weight
0.000
Exact Mass
0.000