250520 | N-DODECYL-ß-D-MALTOSIDE (DDM, 85%)


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N-DODECYL-ß-D-MALTOSIDE (DDM, 85%)

N-DODECYL-ß-D-MALTOSIDE (DDM, 85%)

This product is a more cost-effective alternative to Avandecrys® DDM that can be used for membrane protein extraction and purification.
DDM is the most widely used detergent for the isolation and purification of GPCR’s.
In addition, LacY likely favors a higher-energy intermediate periplasmic-open conformation in situ, but collapses to a lower-energy periplasmic-closed conformation in DDM after purification. It is interesting to note that the branched-chain maltoside detergents stabilize LacY in the membrane-embedded form (see Related Products).

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C24H46O11
Percent Composition
C 56.45%, H 9.08%, O 34.47%
Purity
>85%; contains <15% alpha isomer
Stability
1 Year
Storage Temperature
-20°C
CAS Number
69227-93-6
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
510.615
Exact Mass
510.304
Synonyms
DDM
lauryl maltoside dodecyl
4-O-α-D-glucopyranosyl-β-D-glucopyranoside

Bruggisser J, Tarek B, Wyder M, Müller P, von Ballmoos C, Witz G, Enzmann G, Deutsch U, Engelhardt B, Posthaus H. CD31 (PECAM-1) Serves as the Endothelial Cell-Specific Receptor of Clostridium perfringens β-Toxin. Cell Host Microbe. 2020 Jul 8;28(1):69-78.e6. doi: 10.1016/j.chom.2020.05.003. Epub 2020 Jun 3. PMID: 32497498.

PubMed ID: 32497498