Oxysterols

Oxysterols have been identified as an important class of regulatory molecules with diverse biological actions. These molecules have been found to be natural regulators of sterol synthesis and of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase. Oxysterols can induce programmed cell death and can also affect the development of calcification in vascular cells. Oxysterols are also linked to affecting nuclear orphan receptors. Oxysterols have a significant potential for application in pharmaceutical medicine due to their key roles in cholesterol metabolism, cell growth, and various other biological processes. Avanti offers a wide variety of oxysterols to fit your research needs including both synthetic derivatives and natural oxysterols.

Schroepfer Jr. G. (2000) Oxysterols: Modulators of Cholesterol Metabolism and Other Processes. Phys. Rev. 80:361-554. https://doi.org/10.1152/physrev.2000.80.1.361

  • Fluorinated
    • BUY
      700002 - F7-Cholesterol
  • Sulfonated
    • BUY
      700016 - cholesterol sulfate
    • BUY
      700017 - 25-hydroxycholesterol-3-sulfate
  • Phosphorylated
    • BUY
      700124 - Chol-C10-PC
  • Fluorescent
    • BUY
      810250 - 25-NBD Cholesterol
    • BUY
      810251 - NBD-6 Cholesterol
    • BUY
      810252 - NBD-12 Cholesterol
    • BUY
      810309 - 25-NBD cholest-4-en-3-one
  • Polyunsaturated
    • BUY
      700060 - desmosterol
    • BUY
      700063 - lanosterol
    • BUY
      700068 - zymosterol
    • BUY
      700099 - lanosterol-95
    • BUY
      700114 - 5α-7,24-cholestadiene
    • BUY
      700188 - 14-dehydro zymostenol
    • BUY
      810253 - dehydroergosterol (DHE)
  • Cholestenoic Acid
  • A-ring Substituted
    • BUY
      700036 - 4ß-hydroxycholesterol
    • BUY
      700064 - cholestanol
    • BUY
      700065 - cholestenone
    • BUY
      700079 - zymosterone
    • BUY
      700094 - cholestanol-d5
    • BUY
      700123 - CholPC
    • BUY
      700144 - 15:0 cholesteryl-d7 ester
    • BUY
      700149 - 16:0 cholesteryl-d7 ester
  • B-ring Substituted
    • BUY
      700014 - 5ß,6ß-epoxycholestanol-d7
    • BUY
      700015 - 7-ketocholesterol
    • BUY
      700030 - 6α-hydroxy-5α-cholestanol
    • BUY
      700032 - 5α,6α-epoxycholestanol
    • BUY
      700033 - 5ß,6ß-epoxycholestanol
    • BUY
      700034 - 7α-hydroxycholesterol
    • BUY
      700035 - 7ß-hydroxycholesterol
    • BUY
      700047 - 5α,6α-epoxycholestanol-d7
    • BUY
      700066 - 7-dehydrocholesterol
    • BUY
      700075 - 8(9)-dehydrocholesterol
    • BUY
      700076 - 8(14)-dehydrocholesterol
    • BUY
      700113 - 7α-hydroxycholestenone
    • BUY
      700117 - zymostenol-d7
    • BUY
      700118 - zymostenol
    • BUY
      700138 - 7-dehydrodesmosterol
    • BUY
      700140 - 6-keto-5α-hydroxycholesterol
  • D-ring Substituted
    • BUY
      700008 - 15-ketocholestene
    • BUY
      700009 - 15-ketocholestane
    • BUY
      700010 - 15α-hydroxycholestene
    • BUY
      700011 - 15ß-hydroxycholestene
  • Side Chain Substituted
    • BUY
      700019 - 25-hydroxycholesterol
    • BUY
      700021 - 27-hydroxycholesterol
    • BUY
      700037 - 24(R/S),25-epoxycholesterol
    • BUY
      700039 - 24(S),25-epoxycholesterol
    • BUY
      700048 - 24(R/S),25-epoxycholesterol-d6
    • BUY
      700057 - 22(S)-hydroxycholesterol
    • BUY
      700058 - 22(R)-hydroxycholesterol
    • BUY
      700061 - 24(S)-hydroxycholesterol
    • BUY
      700071 - 24(R)-hydroxycholesterol
    • BUY
      700084 - 27-hydroxy cholestenone
    • BUY
      700122 - campestanol
    • BUY
      700125 - DMHCA
    • BUY
      700135 - 25, 27-dihydroxycholesterol
    • BUY
      700156 - 20α-hydroxycholesterol
    • BUY
      700353 - 24S,25-epoxyzymosterol
    • BUY
      792747 - 24(S/R) 25-epoxylanosterol
  • Double Substituted
    • BUY
      700022 - 7-keto-27-hydroxycholesterol
    • BUY
      700023 - 7α,27-dihydroxy-4-cholesten-3-one
    • BUY
      700024 - 7α,27-dihydroxycholesterol
    • BUY
      700025 - 7ß,27-dihydroxycholesterol
    • BUY
      700054 - 5α,6ß-dihydroxycholestanol
    • BUY
      700077 - FF-MAS
    • BUY
      700080 - 7α,25-dihydroxycholesterol
    • BUY
      700081 - 7β,25-dihydroxycholesterol
    • BUY
      700096 - 7α,24(S)-dihydroxycholesterol
    • BUY
      700098 - 7α,24(S)-dihydroxy-4-cholesten-3-one
    • BUY
      700127 - 7-keto-25-hydroxycholesterol
    • BUY
      700129 - 7α,24S,27-trihydroxycholesterol
    • BUY
      700131 - 24S,27-dihydroxycholesterol
    • BUY
      700378 - 27-Hydroxy Oncosterone
  • Cholestanoic Acid
    • BUY
      700070 - trihydroxycholestanoic acid