Sterols - Deuterated

Plant sterols, also referred to as phytosterols, and stanols, also referred to as phytostanols, have long been studied for their effects on cholesterol levels. Phytosterols are often used in food manufacturing as additives to increase the overall content of phytosterols which can potentially lower LDL cholesterol levels. Some sterols have been studied as potential drug candidates and treatment agents. Phytosterols have been found to have higher degrees of absorption than phytostanols in humans. Stanols have a similar structure to sterols, the only difference being that stanols are saturated at the 5-" ring position.

The use of deuterated molecules can be useful when studying many properties of membrane proteins. This is especially useful for structural biology research and pharmaceutical development. Some of the benefits of using Avanti’s deuterated phospholipids include the simplification of proton nuclear magnetic resonance imaging (NMR) spectra and easier detection of signals from biomolecules in other NMR experiments.

Khaled, R. Stigmasterol medicinal properties: a review. Int. J. Innovative Pharm. Sci. Res. 2020,8, 25-29