Antigenic Lipids

Antigenic reactivity references a virus's ability to bind to specific antibody molecules. Haptens are a type of antigen that elicit the production of antibodies when attached to a carrier molecule. Avanti’s antigenic lipids are made through the conjugation of 16:0 PE and a dinitrophenyl (DNP) or trinitrophenyl (TNP) headgroups. DNP and TNP are both haptens and their lipid conjugates can be used to study antibody binding at lipid membrane interfaces.

Jung, H., Yang, T., Lasagna, M., Shi, J., Reinhart, G., Cremer, P. Impact of hapten presentation on antibody binding at lipid membrane interfaces. Biophysical Journal. 2008; 94: 3094-3103