Diacylglycerol Pyrophosphate (DGPP)

Diacylglycerol pyrophosphate (DGPP) has been found in plants, but not animals. DGPP production seems to be a feature of phosphatidic acid (PA) signaling in plants. DGPP has been shown to activate macrophages to secrete arachidonate metabolites in mammals, even though they are not found naturally in mammals. This mechanism is a key event in the immunoinflammatory response. Studies have shown that DGPP functions to attenuate the PA signal in plants and it is also believed to be a good candidate as a signaling molecule itself.

van Schooten, Bas & Testerink, Christa & Munnik, Teun. (2006). Signaling diacylglycerol pyrophosphate, a new phosphatidic acid metabolite. Biochimica et Biophysica Acta. 1761. 151-9. 10.1016/j.bbalip.2005.12.010.

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      810811 - 18:1 DGPP