The Lipid Lowdown-Potential To Treat Type II Diabetes
NEW ENDOGENOUS LIPID WITH ANTI-DIABETIC AND ANTI-INFLAMMATORY EFFECTS
PAHSA levels correlate highly with insulin sensitivity and are reduced in adipose tissue and serum of insulin-resistant humans. In adipocytes, PAHSAs signal through GPR120 to enhance insulin-stimulated glucose uptake. Thus, FAHFAs are endogenous lipids with the potential to treat type 2 diabetes.
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