Explore the Lipidome: Neurolipidomics Live Webinar Series

Posted on April 17, 2023

Lipid Leaders for Social 1

Hey, all you lipidomics researchers out there! Are you ready for the event of the year? Our second annual Explore the Lipidome LIVE webinar series is just around the corner, and it's going to be bigger and better than ever before!

This year, we're thrilled to welcome three outstanding experts to the stage, each with their own unique perspectives on neurolipidomics research. First up, we have the renowned Dr. Xianlin Han, who will share his groundbreaking research on shotgun lipidomics. Next, we'll be joined by the brilliant Dr. Shane Ellis, who will give us the lowdown on the latest advances in lipidomics technology. And last but not least, Dr. Steffany Bennet bring us a brilliant discussion on lipophenomics of dimentia.

But that's not all - this is a live event, which means you'll have the opportunity to ask questions and engage with our experts in real time. So, what are you waiting for? Grab your lab coat, your favorite mug of coffee, and join us for this exciting event! Registration is now open, so keep reading to register today. We can't wait to see you there!

Part 1: Xianlin Han, PhD, presents "Neurolipidomics revealed the cause of neurogenic bladder in Alzheimer’s disease"

Dr. Xianlin Han is an internationally-renowned investigator in the fields of lipidomics, lipid metabolism, and lipid biochemistry. He has developed expertise in broad areas of research, such as neuroscience, diabetes, and metabolic biochemistry. The mass spectrometric techniques for lipidomics developed by his group, collectively termed “multi-dimensional mass spectrometry-based shotgun lipidomics” with unparalleled high sensitivity and comprehensive coverage, has been widely used to identify altered lipid metabolism, trafficking, and homeostasis, and biomarkers under patho(physio)logical conditions. The current interests of his laboratory research focus on Alzheimer’s disease, diabetic neuropathy, and mitochondrial dysfunction in diabetic hearts. As an investigator or co-investigator on over thirty previous NIH-funded grants, he has successfully produced multiple peer-reviewed publications from each project, resulting in a total of over 300 peer-reviewed publications. He says "It is gratifying that my contributions have received over 34,000 citations (over half are since 2015) with an h-index of 88 (Google Scholar, 2021)."

Part 2: Shane Ellis, PhD, presents "Large Scale Quantitative Imaging Mass Spectrometry of Lipids using MALDI and MALDI-2 using MSI Splash"

Dr. Shane R. Ellis obtained his PhD in ambient ionization mass spectrometry of lipids from the University of Wollongong, Australia in 2013. He then began two-year postdoc at FOM-AMOLF (Amsterdam) working on the development of active pixel detectors for mass spectrometry and ion mobility. In 2014 he was appointed as assistant professor within the Maastricht MultiModal Molecular Institute (M4I) at Maastricht University, where he led the Instrumentation and Application Development group. Here, he established a world-leading group focusing on the development of advanced mass spectrometry imaging methods and their application to studying localized lipid metabolism within tissues. This work included leading several large development projects with mass spectrometry manufacturers. He has pioneered the development of several methods that provide ever-greater structural detail of lipids in imaging experiments, including the resolution of structural isomers. In 2020 he moved to University of Wollongong as an ARC Future Fellow, where he is establishing a mass spectrometry imaging group within the new Molecular Horizons Institute, focusing on both advancing the technology and its application to the life sciences.

Part 3: Steffany Bennett, PhD, presents "Lipophenomics of Dementia: Sex-specific metabolic determinants of risk and resiliency"

Dr. Steffany Bennett is a lipid biochemist and systems neurobiologist working to identify sex, gender- and ethnicity-specific differences in lipid metabolism associated with neurodegenerative disease. She a Full Professor and University Research Chair in Neurolipidomics at the University of Ottawa. She is also the Director of the India Taylor Lipidomics Research Platform, Associate Director of the Centre for Catalysis Research and Innovation, Co-Director of both the NSERC CREATE Matrix Metabolomics Training Program and the CIHR Vascular Dementia Training program (VAST). Her area of expertise is in the use of high-performance liquid chromatography electrospray ionization tandem mass spectrometry as applied to neurolipidomics and to evidence-based personalized precision medicine focusing on how lipid metabolism dictates vulnerability and resilience to genetic determinants of neurodegenerative disease.