In addition to its role in cellular structure, the bioactive sphingolipid, ceramide, has been shown to be important for the regulation of a host of cellular functions including cell growth, proliferation, differentiation, senescence, necrosis, and apoptosis...
Ceramide synthases (CerSs) acylate sphingoid long-chain bases to form (dihydro)ceramides [1]. Mammals contain six distinct CerSs, each of which uses a specific subset of fatty acyl-coenzyme As to produce various subspecies of (dihydro)ceramides...
Dr. Erhard Bieberich's laboratory at Georgia Reagents University is interested in proteins that mediate the regulation of cilia and flagella by ceramide. Flagella and cilia are sensory and motor cellular organelle responsible for moving extracellular fluids and particles and propelling cells and unicellular organisms...
The therapeutic promise of gene therapy in treating and altering disease states has provided significant motivation in developing improved methods to deliver genes to cells [1,2]. Currently, two major classes of gene delivery vectors exist: viral and synthetic...
Avanti’s new Fluorescent Endocannabinoids may be used to map the impact of various treatments and inhibitors on endocannabinoid uptake and distribution in living cells.