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NEW products this week: 9/19/2016
September 21, 2016
14:0 Sphingomyelin. This new SM is one more in the list of sphingomyelins currently in stock………………………………….. Regadenoson or Lexiscan is an A2A adenosine receptor agonist used as a coronary vasodilator in pharmacologic stress testing……………….. C18:1 Lactosyl(ß) Ceramide. This adds to the extensive list of glycosylated sphingolipids and derivatives currently available…………….. Click Read More for links
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Lipids for Liposomes: Selection, Preparation and Application Video
August 15, 2016
Dr. Di Bush gave a presentation at CRS in Seattle, Washington. Her presentation covered the selection, preparation and application of liposomes. To see her full presentation click the link below. The Avanti Formulations Team can help develop a suitable formulation for your liposome or nanoparticle. With the vast library of Avanti lipids and state-of-the-art equipment
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Nanomedicines Symposium: Advances in Materials, Manufacturing & Therapeutic Applications
May 6, 2016
Speakers: Yvonne Perrie | Professor, Aston University Ben Boyd | Professor, Monash University Gaurav Sahay | Asst. Professor, Oregon State University Daniel Siegwart | Asst. Professor, UT Southwestern Kazuo Maruyama | Professor, Teikyo University Priya Karmali | Assoc. Director, Formulation Development, Arturus Therapeutics Don Enns | CEO, Transferra Nanosciences Volker Fehring | Director, Formulation Development,
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The Lipid Lowdown-Potential To Treat Type II Diabetes
April 13, 2016
NEW ENDOGENOUS LIPID WITH ANTI-DIABETIC AND ANTI-INFLAMMATORY EFFECTS PAHSA levels correlate highly with insulin sensitivity and are reduced in adipose tissue and serum of insulin-resistant humans. In adipocytes, PAHSAs signal through GPR120 to enhance insulin-stimulated glucose uptake. Thus, FAHFAs are endogenous lipids with the potential to treat type 2 diabetes. The 141 Edition of the
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Product Spotlight: Fluorescent Endocannabinoids
April 12, 2016
Avanti’s new Fluorescent Endocannabinoids may be used to map the impact of various treatments and inhibitors on endocannabinoid uptake and distribution in living cells. The endocannabinoid pathway influences behavior, lipogenesis, embryologic development, and pathophysiological effects including pain, inflammation, stress, obesity, and non-alcoholic fatty liver disease. Endogenous endocannabinoids including arachidonoylethanolamide (anandamide, AEA) and 2-arachidonoylglycerol (2-AG) are
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Spotlight: MVL5/GMO Delivery System for siRNA/DNA
March 23, 2016
The therapeutic promise of gene therapy in treating and altering disease states has provided significant motivation in developing improved methods to deliver genes to cells [1,2]. Currently, two major classes of gene delivery vectors exist: viral and synthetic [1]. Viral vectors including retroviruses and adenoviruses have the advantage of high gene transfer efficiency; however,
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140th Edition-The Lipid Lowdown
March 11, 2016
New Sterols linked to Atherosclerosis The proatherogenic properties of the cholesterol 5,6-secosterols (atheronal-A and atheronal-B), recently discovered in atherosclerotic arteries, have been investigated in terms of their effects on monocyte/macrophage function. A fluorescent analogue of atheronal-B, when cultured in either aqueous buffer or in media containing fetal calf serum, is rapidly taken-up into cultured macrophage
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Biophysical Society Meeting: February 27- March 2, 2016
February 26, 2016
On February 27- March 2, 2016, The Avanti Roadshow will be at the 60th Annual Biophysical Society Meeting in Los Angeles, CA! Year after year, the Biophysical Society Meeting is a great place that brings together some of the leading scientists from around the world. With over 7,000 attendees and 500 speakers, Avanti loves this
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Spotlight: pacFA Ceramide
February 26, 2016
Dr. Erhard Bieberich’s laboratory at Georgia Reagents University is interested in proteins that mediate the regulation of cilia and flagella by ceramide. Flagella and cilia are sensory and motor cellular organelle responsible for moving extracellular fluids and particles and propelling cells and unicellular organisms [1]. The bioactive sphingolipid, ceramide, has been found to directly interact
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Spotlight: Ceramide Synthase (CerS) Assay Kit
February 26, 2016
Ceramide synthases (CerSs) acylate sphingoid long-chain bases to form (dihydro)ceramides [1]. Mammals contain six distinct CerSs, each of which uses a specific subset of fatty acyl-coenzyme As to produce various subspecies of (dihydro)ceramides [1]. CerSs have become of considerable interest due to the growing involvement of this enzyme family in cell regulation and the pathology
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