Product Spotlight: Understanding the Role of Oxysterols in the Brain

Posted on May 12, 2021


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Oxysterols are an important class of regulatory lipids involved in a wide variety of biological functions. Oxysterols have huge potential in pharmaceutical applications due to their role in cholesterol metabolism, cell growth, and many other biological processes. Chances are slim that you won’t be able to find the oxysterol that you’re looking for on our website. And if you can’t, just contact us about custom synthesizing the oxysterol you need! Keep reading to find out how oxysterols are being used in Alzheimer’s disease and brain sterol homeostasis research right now!

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Research Spotlight: C24:0 and C24:1 Sphingolipids in Cholesterol-Containing, Five- and Six-Component Lipid Membranes

Posted on May 12, 2021


Goni Publication
We hope you had a chance to read our most recent Lipid Leaders Interview with Dr. Felix Goni. In the interview, Dr. Goni gave us some great insight into his research at the University of the Basque Country and Instituto Biofisika. To follow that, we wanted to share one of his recent publications investigating C24:0 and C24:1 Sphingolipids in Cholesterol-Containing, Five- and Six-Component Lipid Membranes. Dr. Goni has been a loyal Avanti customer and friend for many years, and it is always exciting to see what his group accomplishes! Keep reading to learn more!

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Research Spotlight: Sex Differences in Insulin Sensitivity are Related to Muscle Tissue Acylcarnitine But Not Subcellular Lipid Distribution

Posted on April 26, 2021


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Our first May Research Spotlight uses Avanti's Lipidomic Standards to investigate lipid subspecies distribution as a contributor to differences in insulin sensitivity between men and women with obesity. Keep reading to check out the great work going on at University of Colorado Anschutz Medical Campus in Aurora, Colorado!

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Conversations with Lipid Leaders: Dr. Felix Goni

Posted on April 26, 2021


Felix Goni
The Conversations with Lipid Leaders Interview Series brings forward insights and experience from the communities most influential and upcoming scientists to stay connected to current colleagues and inspire the next generation of Lipid Leaders! Keep reading for our interview with Dr. Felix Goni!

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Conversations with Lipid Award Winners: Dr. William Griffiths

Posted on April 19, 2021


Bill Griffiths
We would like to congratulate Dr. William Griffiths on being the recipient of the 2021 the American Oil Chemists’ Society’s Schroepfer Medal which recognizes a scientist who has made significant and distinguished advances in the steroid or sterols field. We caught up with Dr. Griffiths to find out more about his research and what winning the Schroepfer Medal means to him! Keep reading to find out what he had to say!

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Conversations with Avanti Award Winners: Dr. Jean Schaffer

Posted on April 14, 2021


Jean Schaffer
We would like to congratulate Dr. Jean Schaffer on being the recipient of the 2020/2021 American Society for Biochemistry and Molecular Biology Avanti Award in Lipids for her pioneering work in understanding and preventing lipotoxicity. We caught up with Dr. Schaffer to find out more about her research and what winning the Avanti Award means to her! Keep reading to find out what she had to say!

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Conversations with Avanti Award Winners: Dr. Jeremy Baskin

Posted on April 14, 2021


Jeremy Baskin
We would like to congratulate Dr. Jeremy Baskin on being the recipient of the 2020/2021 ASBMB Walter A. Shaw Young Investigator in Lipid Research Award unique blend of chemical biology, biochemistry, and cell biology approaches to develop innovative methods for imaging and probing various classes of lipids in vivo. We caught up with Dr. Baskin to find out more about his research and what winning the Walter A. Shaw Young Investigator Award means to him! Keep reading to find out what he had to say!

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Research Spotlight: Investigating the Impact of Delivery System Design on the Efficacy of Self-Amplifying RNA Vaccines

Posted on April 12, 2021


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We hope you had a chance to read our most recent Lipid Leaders Interview with Dr. Yvonne Perrie. In the interview, Dr. Perrie gave us some great insight into her current research. To follow that, we wanted to share one of her recent publications investigating the impact of different delivery systems on the efficacy of self-amplifying mRNA (SAM) vaccines. Dr. Perrie and her team prepared and compared four different cationic SAM delivery platforms including liposomes, solid lipid nanoparticles (SLNs), polymeric nanoparticles (NPs), and emulsions. These lipid-based delivery platforms were prepared using Avanti’s DOTAP and DDA products. Keep reading to find out what this investigation uncovered!

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Research Spotlight: Lipopolymers and Lipids from Lung Surfactants in Association with N-acetyl-l-cysteine: Characterization and Cytotoxicity

Posted on March 30, 2021


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Our first April Research Spotlight comes from Nadia Chiaramoni. Nadia connected with us on Twitter and shared one of her recent works where she utilized our diacetylene lipids to form polymeric liposomes as a possible N-acetyl-I-cysteine (NAC) delivery system. Keep reading to check out Nadia’s publication in the Chemistry and Physics of Lipids journal and the great work that she is doing at the Universidad Nacional de Quilmes in Buenos Aires, Argentina.

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Conversations with Avanti Award Winners: Dr. Richard Pastor

Posted on March 27, 2021


Richard Pastor
We would like to congratulate Dr. Richard Pastor on being the recipient of the 2021 Biophysical Society Avanti Award in Lipids for his pioneering Molecular Dynamics Simulations of lipids and the development of the widely used lipid forcefield. We caught up with Dr. Pastor to find out more about his research and what winning the Avanti Award means to him! Keep reading to find out what he had to say!

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Conversations with Lipid Leaders: Professor Yvonne Perrie

Posted on March 22, 2021


Yvonne Perrie
The Conversations with Lipid Leaders Interview Series brings forward insights and experience from the communities most influential and upcoming scientists to stay connected to current colleagues and inspire the next generation of Lipid Leaders! Keep reading for our interview with Professor Yvonne Perrie!

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Research Spotlight: Deep Mining of Oxysterols and Cholestenoic Acids in Human Plasma and Cerebrospinal Fluid: Quantification using Isotope Dilution Mass Spectrometry

Posted on March 15, 2021


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Our second citation promotion for March comes from Dr. William Griffiths at Swansea University Medical School in Wales. Dr. Griffiths and his team of collaborators used Avanti’s oxysterolSPLASH and individual oxysterol standards to develop methodology to identify and quantify multiple sterols (oxysterols and sterol-acids) in plasma and cerebrospinal fluid. Avanti’s own, Lisa Connell, Director of the Lipidomics Division, is included as an author on the paper for her work in developing these standards. Keep reading to learn more about this exciting work!

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Division Spotlight: Formulations

Posted on March 15, 2021


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Amy Druschitz, Production Manager for the Formulations Division, took time to chat with us and provide insight into the Avanti's Formulations Division! Keep reading to learn more!

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Conversations with Lipid Leaders: Dr. Dan Raben

Posted on February 22, 2021


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The Conversations with Lipid Leaders Interview Series brings forward insights and experience from the communities most influential and upcoming scientists to stay connected to current colleagues and inspire the next generation of Lipid Leaders! Keep reading for our interview with Dr. Dan Raben!

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Research Spotlight: Mono- and Poly-unsaturated Phosphatidic Acid Regulates Distinct Steps of Regulated Exocytoses in Neuroendocrine Cells

Posted on February 16, 2021


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We would like to thank Nick Vitale from the Universite de Strasbourg in France for submitting this publication to the Citation Promotion Contest! Nick and his team are loyal customers of Avanti, and it’s exciting to see what they have been able to accomplish in the work titled “Mono- and Poly-Unsaturated Phosphatidic Acid Regulates Distinct Steps of Regulated Exocytoses in Neuroendocrine Cells.” Keep reading for more!

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Product Spotlight: Exclusive Detergents

Posted on February 16, 2021


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Avanti is in no short supply of products to aid in your projects and applications. This month, we are taking a closer look at Avanti’s Exclusive Detergents for your protein crystallography research.

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Research Spotlight: Using Avanti LIPIDOMIX® Standards to Create Lipidomics Software

Posted on February 01, 2021


Mass Spectrometry
As we continue our Citation Promotion series, check out how Jeremy Koelmel and his research team use Avanti LIPIDOMIX® Standards to create lipidomics software for the semi-quantification of lipids! They have released the LipidMatch Flow, LipidMatch Normalizer, and Lipid Annotator software platforms. Keep reading to find out how to access their software and how you can use it for analysis in your lipidomics research!

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Research Spotlight: Localization of Cyclopropane Modifications in Bacterial Lipids via 213 nm Ultraviolet Photodissociation Mass Spectrometry

Posted on January 21, 2021


Mass Spectrometry
Check out this exciting research submitted, as part of our Citation Promotion, by Molly Blevins from the Department of Chemistry, University of Texas at Austin! The work is titled “Localization of Cyclopropane Modifications in Bacterial Lipids via 213 nm Ultraviolet Photodissociation Mass Spectrometry”. Molly and the rest of the Brodbelt research group were able to employ 213 nm ultraviolet photodissociation mass spectrometry (UVPD-MS) for structural characterization of cyclopropane rings in bacterial phospholipids and mycolic acids.

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MRI Contrasting Agents: Broader Applications

Posted on January 08, 2021


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Magnetic resonance imaging (MRI) is one of the top ten most common medical diagnostic tests conducted around the world with tens of millions of contrast enhanced MRI exams performed annually. Read on to find out how Avanti Lipids are being used in these routine procedures!

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Product Spotlight: Photoswitchable Lipids

Posted on December 10, 2020


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Until recently lipidomics has been overshadowed by advancements in proteomics and genomics technologies. Research related to lipidome analysis over the last several years has given a greater insight and understanding of the roles that lipids play in biochemistry.

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MRI Contrasting Agents: Broader Applications

Posted on December 03, 2020


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Magnetic resonance imaging (MRI) is one of the top ten most common medical diagnostic tests conducted around the world with tens of millions of contrast enhanced MRI exams performed annually. Contrasting agents are used for MRI exams to enhance diagnostic accuracy and information that often cannot be obtained from other noninvasive techniques.

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The Latest From Avanti

Posted on October 08, 2020


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It’s been business as usual this month at Avanti—which means we’ve been busy brewing up new products for R&D and more! Keep reading for October 2020 news.

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The Latest From Avanti

Posted on September 08, 2020


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Busy season hasn’t shown any signs of slowing this September. In fact, Avanti has been abuzz with news that we’ve been more than itching to share. Read on!

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The Latest From Avanti

Posted on August 11, 2020


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As usual, Avanti has had a busy August! Keep reading to find out what we’ve been up to—including products featured in peer-reviewed journals and job opportunities.

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Avanti Polar Lipids Agrees to be Acquired by Croda

Posted on July 06, 2020


Avanti Polar Lipids, Inc. (“Avanti” or the “Company”) today announces it has agreed to be acquired by Croda International, Plc (“Croda”). The combination of two life science leaders brings together Avanti’s expertise in lipid-based drug delivery solutions through its research products and pharmaceutical services and Croda’s range of life science products and cGMP manufacturing capabilities to expand their respective breadth of products and services for biotechnology businesses, academic institutions and pharmaceutical companies globally.

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New Product Spotlight: Detergents

Posted on May 12, 2020


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In this month’s New Product Spotlight, we’re highlighting our detergents! Keep reading for a list of some of Avanti’s unique detergents and how to utilize them in your research.

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Product Spotlight: Adjuvants

Posted on April 09, 2020


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Avanti is ready to support your adjuvant formulation development activities and continue working toward more effective adjuvants and adjuvant combinations to support global health strategies and prevent future pandemics. Keep reading for more information.

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Meet the Winners of the Avanti Awards

Posted on April 02, 2020


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Keep reading to learn about the ASBMB Avanti Award in Lipids, the ASBMB Walter Shaw Young Investigator Award, and the MSACL Catherine E. Costello Award for Females in Mass Spectrometry, and their winners.

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New Product Spotlight: IsoPure

Posted on March 10, 2020


Iso Pure
Avanti Polar Lipids is excited to announce that IsoPure phospholipids are now available! Find out more about our new line of products, and what they can do for your research.

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Why Lipidomics is so Important

Posted on March 05, 2020


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The subgroup of lipidomics is developing rapidly into a discipline of its own, thanks to the fresh perspective it’s bringing to the scientific community. Read more about its applications here.

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Where in the World is Walt?

Posted on December 05, 2019


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Our founder, Dr. Walter A. Shaw, is on the move for the month of December! Find out what conferences he’s attending and where in our latest Where in the World is Walt?

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Product Spotlight: SPLASH

Posted on October 08, 2019


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Our product spotlight is on SPLASH. Read about all the benefits this product can bring to your research, and visit our website to place an order.

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Where in the World is Walt?

Posted on October 03, 2019


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Find out what our founder, Walt Shaw, is up to for the month of October! As usual, he’s traveling a lot, and getting to attend some fascinating conferences.

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2019 ASBMB Award Winner

Posted on April 02, 2019


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Every year, Avanti sponsors the ASBMB awards, which honor the leaders in the field of lipid science. Find out more about this year’s winners here!

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Avanti and the Membrane Chix

Posted on March 12, 2019


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We at Avanti are lucky to have fostered a relationship with the Membrane Chix, a group of scientists, primarily women, who are faithful Avanti lipid users. Learn more here.

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The Culture of Avanti

Posted on January 08, 2019


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At Avanti, we believe in the work of creating the highest purity lipids, and we believe in the team that makes the work possible. Read on to learn more about our culture!

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How Can We Help?

Posted on May 31, 2018


For 50 years, we have made it our mission to provide research and pharmaceutical scientists with the highest purity products. We offer solutions for the entire product cycle-Research to Commercialization. We are dedicated to providing excellent customer service every step of the way! Whether searching for products, placing an order, or taking advantage of our custom synthesis service, please reach out to us during any part of the ordering process. We are here to help!

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Spotlight: Ceramide Delivery System

Posted on February 21, 2018


In addition to its role in cellular structure, the bioactive sphingolipid, ceramide, has been shown to be important for the regulation of a host of cellular functions including cell growth, proliferation, differentiation, senescence, necrosis, and apoptosis...

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Spotlight: Ceramide Synthase (CerS) Assay Kit

Posted on February 21, 2018


Ceramide synthases (CerSs) acylate sphingoid long-chain bases to form (dihydro)ceramides [1]. Mammals contain six distinct CerSs, each of which uses a specific subset of fatty acyl-coenzyme As to produce various subspecies of (dihydro)ceramides...

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Spotlight: pacFA Ceramide

Posted on February 21, 2018


Dr. Erhard Bieberich's laboratory at Georgia Reagents University is interested in proteins that mediate the regulation of cilia and flagella by ceramide. Flagella and cilia are sensory and motor cellular organelle responsible for moving extracellular fluids and particles and propelling cells and unicellular organisms...

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Biophysical Society Meeting: February 27- March 2, 2016

Posted on February 21, 2018


On February 27- March 2, 2016, The Avanti Roadshow will be at the 60th Annual Biophysical Society Meeting in Los Angeles, CA! Year after year, the Biophysical Society Meeting is a great place that brings together some of the leading scientists from around the world. With over 7,000 attendees and 500 speakers, Avanti loves this meeting because it still maintains the “small meeting” feel. It is a great place for learning and networking.

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140th Edition-The Lipid Lowdown

Posted on February 21, 2018


The proatherogenic properties of the cholesterol 5,6-secosterols (atheronal-A and atheronal-B), recently discovered in atherosclerotic arteries, have been investigated in terms of their effects on monocyte/macrophage function. A fluorescent analogue of atheronal-B, when cultured in either aqueous buffer or in media containing fetal calf serum, is rapidly taken-up into cultured macrophage cells and accumulates at perinuclear sites...

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Spotlight: MVL5/GMO Delivery System for siRNA/DNA

Posted on February 21, 2018


The therapeutic promise of gene therapy in treating and altering disease states has provided significant motivation in developing improved methods to deliver genes to cells [1,2]. Currently, two major classes of gene delivery vectors exist: viral and synthetic...

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