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Posted on May 31, 2018


For 50 years, we have made it our mission to provide research and pharmaceutical scientists with the highest purity products. We offer solutions for the entire product cycle-Research to Commercialization. We are dedicated to providing excellent customer service every step of the way! Whether searching for products, placing an order, or taking advantage of our custom synthesis service, please reach out to us during any part of the ordering process. We are here to help!

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Spotlight: Ceramide Delivery System

Posted on February 21, 2018


In addition to its role in cellular structure, the bioactive sphingolipid, ceramide, has been shown to be important for the regulation of a host of cellular functions including cell growth, proliferation, differentiation, senescence, necrosis, and apoptosis...

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Spotlight: Ceramide Synthase (CerS) Assay Kit

Posted on February 21, 2018


Ceramide synthases (CerSs) acylate sphingoid long-chain bases to form (dihydro)ceramides [1]. Mammals contain six distinct CerSs, each of which uses a specific subset of fatty acyl-coenzyme As to produce various subspecies of (dihydro)ceramides...

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Spotlight: pacFA Ceramide

Posted on February 21, 2018


Dr. Erhard Bieberich's laboratory at Georgia Reagents University is interested in proteins that mediate the regulation of cilia and flagella by ceramide. Flagella and cilia are sensory and motor cellular organelle responsible for moving extracellular fluids and particles and propelling cells and unicellular organisms...

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Biophysical Society Meeting: February 27- March 2, 2016

Posted on February 21, 2018


On February 27- March 2, 2016, The Avanti Roadshow will be at the 60th Annual Biophysical Society Meeting in Los Angeles, CA! Year after year, the Biophysical Society Meeting is a great place that brings together some of the leading scientists from around the world. With over 7,000 attendees and 500 speakers, Avanti loves this meeting because it still maintains the “small meeting” feel. It is a great place for learning and networking.

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140th Edition-The Lipid Lowdown

Posted on February 21, 2018


The proatherogenic properties of the cholesterol 5,6-secosterols (atheronal-A and atheronal-B), recently discovered in atherosclerotic arteries, have been investigated in terms of their effects on monocyte/macrophage function. A fluorescent analogue of atheronal-B, when cultured in either aqueous buffer or in media containing fetal calf serum, is rapidly taken-up into cultured macrophage cells and accumulates at perinuclear sites...

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Spotlight: MVL5/GMO Delivery System for siRNA/DNA

Posted on February 21, 2018


The therapeutic promise of gene therapy in treating and altering disease states has provided significant motivation in developing improved methods to deliver genes to cells [1,2]. Currently, two major classes of gene delivery vectors exist: viral and synthetic...

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The Lipid Lowdown-Potential To Treat Type II Diabetes

Posted on February 21, 2018


PAHSA levels correlate highly with insulin sensitivity and are reduced in adipose tissue and serum of insulin-resistant humans. In adipocytes, PAHSAs signal through GPR120 to enhance insulin-stimulated glucose uptake. Thus, FAHFAs are endogenous lipids with the potential to treat type 2 diabetes.

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147th Edition of the Avanti Newsletter

Posted on February 21, 2018


Whether you are looking for phospholipids, sphingolipids, sterols, or any other of our numerous product offerings, Avanti’s research products are the highest purity lipids on the market and give you the best possibility for success.

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NEW products this week: 10/17/2017

Posted on February 21, 2018


Deuterated Hydroxy Phytosphingosine (S & R), Deuterated Hydroxy Ceramide (S & R), Deuterated Hydroxy Sphinganine (S & R), Deuterated Phytosphingosine. Deuterated Hydroxy Sphingosine...

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This week in research: March 29, 2017

Posted on February 21, 2018


Researchers from Northwest University (Xi’an, Shaanxi, China) used numerous lipid analytical standards from Avanti in a serum lipidomic analysis using UPLC-QTOF/HDMS to study lipid metabolism in chronic kidney disease (CKD). This interesting work identifies profound changes in lipid metabolites in individuals with CKD...

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This week in research: April 5, 2017

Posted on February 21, 2018


People do Amazing Things with Our Lipids! Researchers from the National Center for Global Health and Medicine (Tokyo, Japan) are studying the role of PAF signaling in neuropathic pain, a chronic pain condition resulting from injury of the peripheral or central nervous systems. PAF, as well as, ATP and lyophosphatidic acid are thought to be central mediators of neuropathic pain.

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