News | Avanti Polar Lipids

Research Spotlight: Formation of Tubules and Helical Ribbons by Ceramide Phosphoethanolamine-Containing Membranes

Posted on March 01, 2021

Thank you to Toshi Kobayashi from the Université de Strasbourg for submitting this fascinating work and for choosing Avanti’s lipid products to conduct this research. Check out what Avanti’s ultra pure lipid products made possible this time!

Conversations with Lipid Leaders: Dr. Dan Raben

Posted on February 22, 2021

The Conversations with Lipid Leaders Interview Series brings forward insights and experience from the communities most influential and upcoming scientists to stay connected to current colleagues and inspire the next generation of Lipid Leaders! Keep reading for our interview with Dr. Dan Raben!

Research Spotlight: Mono- and Poly-unsaturated Phosphatidic Acid Regulates Distinct Steps of Regulated Exocytoses in Neuroendocrine Cells

Posted on February 16, 2021

We would like to thank Nick Vitale from the Universite de Strasbourg in France for submitting this publication to the Citation Promotion Contest! Nick and his team are loyal customers of Avanti, and it’s exciting to see what they have been able to accomplish in the work titled “Mono- and Poly-Unsaturated Phosphatidic Acid Regulates Distinct Steps of Regulated Exocytoses in Neuroendocrine Cells.” Keep reading for more!

Product Spotlight: Exclusive Detergents

Posted on February 16, 2021

Avanti is in no short supply of products to aid in your projects and applications. This month, we are taking a closer look at Avanti’s Exclusive Detergents for your protein crystallography research.

Research Spotlight: Using Avanti LIPIDOMIX® Standards to Create Lipidomics Software

Posted on February 01, 2021

As we continue our Citation Promotion series, check out how Jeremy Koelmel and his research team use Avanti LIPIDOMIX® Standards to create lipidomics software for the semi-quantification of lipids! They have released the LipidMatch Flow, LipidMatch Normalizer, and Lipid Annotator software platforms. Keep reading to find out how to access their software and how you can use it for analysis in your lipidomics research!

Research Spotlight: Localization of Cyclopropane Modifications in Bacterial Lipids via 213 nm Ultraviolet Photodissociation Mass Spectrometry

Posted on January 21, 2021

Check out this exciting research submitted, as part of our Citation Promotion, by Molly Blevins from the Department of Chemistry, University of Texas at Austin! The work is titled “Localization of Cyclopropane Modifications in Bacterial Lipids via 213 nm Ultraviolet Photodissociation Mass Spectrometry”. Molly and the rest of the Brodbelt research group were able to employ 213 nm ultraviolet photodissociation mass spectrometry (UVPD-MS) for structural characterization of cyclopropane rings in bacterial phospholipids and mycolic acids.

Research Spotlight: Halogenation-Dependent Effects of the Chlorosulfolipids of Ochromonas danica on Lipid Bilayers

Posted on January 08, 2021

We’re kicking off 2021 with a submission from Frank Moss! Read more about this exciting research entitled: “Halogenation-Dependent Effects of the Chlorosulfolipids of Ochromonas danica on Lipid Bilayers”.

MRI Contrasting Agents: Broader Applications

Posted on January 08, 2021

Magnetic resonance imaging (MRI) is one of the top ten most common medical diagnostic tests conducted around the world with tens of millions of contrast enhanced MRI exams performed annually. Read on to find out how Avanti Lipids are being used in these routine procedures!

Adjuvants May Help Produce a More Effective COVID-19 Vaccine

Posted on January 05, 2021

Clinical trials are seeing an impressive count of the COVID-19 vaccine in development. Now, adjuvants have researchers even more energized.

Product Spotlight: Photoswitchable Lipids

Posted on December 10, 2020

Until recently lipidomics has been overshadowed by advancements in proteomics and genomics technologies. Research related to lipidome analysis over the last several years has given a greater insight and understanding of the roles that lipids play in biochemistry.

Adjuvants: Possible Key to COVID-19 Vaccines

Posted on December 08, 2020

Adjuvants have been of particular interest for the development of a COVID-19 vaccine and several experts postulated that adjuvants would play a key role in shortening the race to find an effective and safe vaccine.

New Research Featuring E06

Posted on December 04, 2020

Our citation promotion is in full swing! Thank you to everyone who submitted articles and presentations!

MRI Contrasting Agents: Broader Applications

Posted on December 03, 2020

Magnetic resonance imaging (MRI) is one of the top ten most common medical diagnostic tests conducted around the world with tens of millions of contrast enhanced MRI exams performed annually. Contrasting agents are used for MRI exams to enhance diagnostic accuracy and information that often cannot be obtained from other noninvasive techniques.

New Product Spotlight: Cationic Lipids

Posted on December 01, 2020

This month’s product spotlight features cationic lipids, which are versatile and easily utilized. Learn about how we can help your liposomal transfection R&D.

NMR-based Metabolomics Helps with Diagnosis of Breast Cancer

Posted on November 05, 2020

Metabolomics may hold an informative bearing throughout cancer’s chronology. It may betray key cancer-linked biomarkers, along with molecular changes.

New Product Spotlight: Detergent Kits

Posted on November 03, 2020

Avanti welcomes a new product to our lineup: detergent kits. These kits offer high levels of purity and a common theme sure to cycle into your R&D.

New Product Spotlight: Detergent Kits

Posted on November 03, 2020

Avanti welcomes a new product to our lineup: detergent kits. These kits offer high levels of purity and a common theme sure to cycle into your R&D.

The Latest From Avanti

Posted on October 08, 2020

It’s been business as usual this month at Avanti—which means we’ve been busy brewing up new products for R&D and more! Keep reading for October 2020 news.

Type 1 Diabetes Preceded by Pro-Inflammatory Lipids in Children

Posted on October 06, 2020

Signaling that underpins type 1 diabetes has proven elusive, but new lipids research may give way to breakthrough. One lipid profile shows key links.

The Latest From Avanti

Posted on September 08, 2020

Busy season hasn’t shown any signs of slowing this September. In fact, Avanti has been abuzz with news that we’ve been more than itching to share. Read on!

What’s New At Avanti? Eicosanoids And Prostaglandins

Posted on September 03, 2020

No stranger to products geared toward ground-breaking research, Avanti is proud to offer eicosanoids and prostaglandins at unrivaled levels of purity.

Sphingolipids: The Key to Understanding Zika Virus

Posted on September 01, 2020

Public health breakthroughs may hinge on research involving sphingolipids, along with their links to Zika virus. These lipids may mean a lot for medicine. Read more here.

The Latest From Avanti

Posted on August 11, 2020

As usual, Avanti has had a busy August! Keep reading to find out what we’ve been up to—including products featured in peer-reviewed journals and job opportunities.

Product Spotlight: Bacterial Lipids

Posted on August 06, 2020

Whatever you need for your next research project, we can deliver the goods. Keep reading for more information on our bacterial lipid products.

The Latest from Avanti

Posted on July 07, 2020

As usual, Avanti has had a busy July! Keep reading to find out what we’ve been up to—including new products and job opportunities.

A Letter to Our Valued Customers: The Next Chapter in Avanti’s Future

Posted on July 06, 2020

As a valued customer of Avanti Polar Lipids, we are pleased to inform you that we have been acquired by Croda International Plc (Croda), a leading speciality ingredient supplier with a strong footprint in pharmaceuticals.

Avanti Polar Lipids Agrees to be Acquired by Croda

Posted on July 06, 2020

Avanti Polar Lipids, Inc. (“Avanti” or the “Company”) today announces it has agreed to be acquired by Croda International, Plc (“Croda”). The combination of two life science leaders brings together Avanti’s expertise in lipid-based drug delivery solutions through its research products and pharmaceutical services and Croda’s range of life science products and cGMP manufacturing capabilities to expand their respective breadth of products and services for biotechnology businesses, academic institutions and pharmaceutical companies globally.

New Product Spotlight: UltimateSPLASH Individual Lipid Class Mixtures

Posted on July 02, 2020

Our latest new product spotlight is all about UltimateSPLASH ONE, and all the individual internal standard mixtures we offer! Keep reading for more information.

The Latest News from Avanti Polar Lipids

Posted on June 09, 2020

As always, Avanti Polar Lipids has been hard at work over the last few months! Here’s what we’ve been up to, including new products, peer-reviewed references, and job opportunities.

Using Metabolomics to Find a SARS-CoV-2 Biomarker

Posted on June 04, 2020

Before you can accurately test for COVID-19, you need to have a biomarker that indicates if a person is sick or not. Keep reading to learn about metabolomics’ important role in COVID-19 research.

New Product Spotlight: MAG Products

Posted on June 02, 2020

In this month’s new product spotlight, we’re highlighting our monoacylglycerol (MAG) products and their role in lipid mesophase crystallization. Keep reading for more information!

New Product Spotlight: Detergents

Posted on May 12, 2020

In this month’s New Product Spotlight, we’re highlighting our detergents! Keep reading for a list of some of Avanti’s unique detergents and how to utilize them in your research.

cGMP and GMP: What’s the Difference?

Posted on May 07, 2020

GMP refers to a set of guidelines created by the FDA to ensure all products are safe, pure, and high quality. So what is cGMP? And which one does Avanti adhere to?

The Latest News from Avanti

Posted on May 05, 2020

While we’ve been staying safe, we’ve also been hard at work. Keep reading for the latest news from Avanti, including new products and job openings.

Leading Research from the European Journal of Lipid Science and Technology

Posted on May 01, 2020

Learn more by checking out the new Lipidomics e-book produced by the collaboration of MilliporeSigma and Wiley Online Learning Library!

Product Spotlight: Adjuvants

Posted on April 09, 2020

Avanti is ready to support your adjuvant formulation development activities and continue working toward more effective adjuvants and adjuvant combinations to support global health strategies and prevent future pandemics. Keep reading for more information.

The Best Way to Kill COVID-19 Is Simpler Than You Might Think

Posted on April 07, 2020

Disinfectants, liquids, wipes, and gels containing alcohol are great at getting rid of viruses—but they aren’t as effective as what’s sitting by your bathroom sink: soap.

Meet the Winners of the Avanti Awards

Posted on April 02, 2020

Keep reading to learn about the ASBMB Avanti Award in Lipids, the ASBMB Walter Shaw Young Investigator Award, and the MSACL Catherine E. Costello Award for Females in Mass Spectrometry, and their winners.

Avanti Update: Impact of the Coronavirus (COVID-19) on Our Operations

Posted on March 31, 2020

Amid the ongoing COVID-19 pandemic, Avanti’s top priority is the health, safety and well-being of our clients and employees.

Avanti Polar Lipids Visitor Policy: Statement Regarding Coronavirus Outbreak (COVID-19)

Posted on March 12, 2020

In an effort to protect against the novel coronavirus known as SARS-CoV-2, which causes the illness known as COVID-19, Avanti is limiting access to its facilities to essential personnel only, and has implemented certain visitor protocols as an interim measure.

New Product Spotlight: IsoPure

Posted on March 10, 2020

Avanti Polar Lipids is excited to announce that IsoPure phospholipids are now available! Find out more about our new line of products, and what they can do for your research.

Why Lipidomics is so Important

Posted on March 05, 2020

The subgroup of lipidomics is developing rapidly into a discipline of its own, thanks to the fresh perspective it’s bringing to the scientific community. Read more about its applications here.

Avanti’s March Road Shows

Posted on March 03, 2020

The Avanti team is looking forward to a very busy March! Keep reading for all of the great conferences and meetings we’re attending this month.

New Product Spotlight: Bile Acids

Posted on February 11, 2020

Avanti Polar Lipids is excited to announce our new line of bile acids! Keep reading for more about our products and their applications.

Systems for Treatment of Bacterial Infections Developed Using Lipid-Based Antimicrobial Delivery

Posted on February 06, 2020

Read about the advantages of lipid-based antimicrobial delivery systems in the treatment of infectious biofilms in our latest blog.

Avanti’s February Road Shows

Posted on February 04, 2020

The Avanti team is looking forward to a very busy February! Keep reading for all of the great conferences and meetings we’re attending this month.

Product Spotlight: UltimateSPLASH ONE

Posted on January 09, 2020

Our new product, UltimateSPLASH ONE, was created to address the need for a comprehensive set of internal standards to allow for accurate quantitation. Read on for more.

Where in the World is Walt?

Posted on December 05, 2019

Our founder, Dr. Walter A. Shaw, is on the move for the month of December! Find out what conferences he’s attending and where in our latest Where in the World is Walt?

How to Prepare Multilamellar Liposomes (LMV)

Posted on December 03, 2019

At Avanti, we’re always trying to help our clients streamline their research. That’s why we created this outline for preparing multilamellar liposomes (LMV). Keep reading for more!

Product Spotlight: 3D-PHAD

Posted on November 12, 2019

Our latest product spotlight is on 3D-PHAD. Keep reading for more information on this product, its applications, and licensing opportunities.

Where in the World is Walt?

Posted on November 07, 2019

Find out what our founder, Dr. Walter A. Shaw, is up to this November! He’s attending some very exciting events. Read on for details.

Product Spotlight: SPLASH

Posted on October 08, 2019

Our product spotlight is on SPLASH. Read about all the benefits this product can bring to your research, and visit our website to place an order.

Where in the World is Walt?

Posted on October 03, 2019

Find out what our founder, Walt Shaw, is up to for the month of October! As usual, he’s traveling a lot, and getting to attend some fascinating conferences.

What to Consider When Selecting Lipids for Drug Delivery or Pharmaceutical Applications

Posted on October 01, 2019

To ensure the success of your project, there are some things you should consider before selecting lipids for drug delivery or pharmaceutical applications. Read on.

SUV vs. LUV: What's the Difference?

Posted on October 01, 2019

Having the right resources is essential to successful research. We’re going over SUV and LUV, what their differences are & which is right for your research.

Product Spotlight: equiSPLASH

Posted on September 10, 2019

Our product spotlight is on EquiSPLASH. Read about all the benefits this product can bring to your research, and visit our website to place an order.

Highlight: cGMP Manufacturing

Posted on September 05, 2019

We are interested in quality development strategies. Keep reading to learn more about cGMP manufacturing and Avanti's unique approach to the process.

Where in the World is Walt?

Posted on September 03, 2019

Walt is traveling to Sapporo, Japan this month for the Liposome Research Days meeting from September 15-18. Keep reading for more about the event!

Where in the World is Walt?

Posted on August 06, 2019

Walt is on the move as usual this August! Read on to find out which international symposium he’s attending, and what he’ll bring back to Avanti.

Highlight: Avanti's Research & Custom Projects Division

Posted on August 01, 2019

We're highlighting our research and custom projects division! We pride ourselves on delivering custom lipids with our signature quality. Keep reading for more info!

The Analytical Center of Excellence

Posted on July 04, 2019

Identification of the lipids in a sample is critical for any lipid researcher, and Avanti can ensure you get successful, reproducible results. Read on.

Cholesterol in Liposomes

Posted on July 02, 2019

The isolation of cholesterol was first performed by Dr. Francois Poulletier de la Salle in 1758. Keep reading for more history and information.

Where in the World is Walt this Summer?

Posted on June 06, 2019

Walt is on the move for the months of June and July. Read on to find out which meetings and conferences he'll be attending this summer!

Establishing Reference Values for Lipids in the Blood

Posted on June 04, 2019

The field of lipidomics research has begun the pursuit of standardization by establishing reference values. Read on to learn how.

Where in the World is Walt this May?

Posted on May 07, 2019

Our founder, Walter (Walt) Shaw, is always on the move to speak and learn in the lipid community. Read on to find out where to find Walt this May!

AOCS 2019 Avanti Lunch & Learn Seminar

Posted on April 08, 2019

We invite you to the Avanti Lipids Lunch & Learn Seminar on Tuesday, May 7th at the Annual AOCS Meeting in St. Louis. Read on to find out more!

Where in the World is Walt?

Posted on April 04, 2019

Our founder, Walt Shaw, travels frequently to advance the work we do in lipid biophysics. Find out what he’ll be up to in the month of April here!

2019 ASBMB Award Winner

Posted on April 02, 2019

Every year, Avanti sponsors the ASBMB awards, which honor the leaders in the field of lipid science. Find out more about this year’s winners here!

ASMS 2019 Avanti Lipids Breakfast Seminar

Posted on March 21, 2019

We invite you to the Avanti Lipids Breakfast Seminar on Wednesday, June 5th at the Annual ASMS Meeting in Atlanta. Read on to find out more!

Avanti and the Membrane Chix

Posted on March 12, 2019

We at Avanti are lucky to have fostered a relationship with the Membrane Chix, a group of scientists, primarily women, who are faithful Avanti lipid users. Learn more here.

Where in the World is Walt?

Posted on March 05, 2019

Our founder, Walt Shaw, is always on the move to promote the work we do in lipid biophysics. Read on to learn what he will be up to in March!

Solvent Challenges Associated with the Storing and Extraction of Lipids

Posted on February 07, 2019

From problem solving to new product development, the devil is in the details with lipid mass spectrometry. Read on with Avanti Polar Lipids.

Avanti: the Highest Quality Lipids for Research

Posted on February 05, 2019

Scientists studying the role of and analyzing quantities of lipids in biological processes need the highest quality reagents and standards for research. Fortunately, that’s what Avanti provides.

The Culture of Avanti

Posted on January 08, 2019

At Avanti, we believe in the work of creating the highest purity lipids, and we believe in the team that makes the work possible. Read on to learn more about our culture!

Mass Spectrometric Approaches to Lipidomic Studies

Posted on January 03, 2019

As explained in this tech talk from renown lipidomic expert Dr. Robert Murphy, there are three main mass spectrometric approaches that each have their benefits and drawbacks.

Research Spotlight: New Technologies Shed Light on Caveolae

Posted on June 04, 2018

Exciting new functions for the small (50-100 nm) cellular invaginations, known as caveolae, are being understood!

How Can We Help?

Posted on May 31, 2018

For 50 years, we have made it our mission to provide research and pharmaceutical scientists with the highest purity products. We offer solutions for the entire product cycle-Research to Commercialization. We are dedicated to providing excellent customer service every step of the way! Whether searching for products, placing an order, or taking advantage of our custom synthesis service, please reach out to us during any part of the ordering process. We are here to help!

Spotlight: Ceramide Delivery System

Posted on February 21, 2018

In addition to its role in cellular structure, the bioactive sphingolipid, ceramide, has been shown to be important for the regulation of a host of cellular functions including cell growth, proliferation, differentiation, senescence, necrosis, and apoptosis...

Spotlight: Ceramide Synthase (CerS) Assay Kit

Posted on February 21, 2018

Ceramide synthases (CerSs) acylate sphingoid long-chain bases to form (dihydro)ceramides [1]. Mammals contain six distinct CerSs, each of which uses a specific subset of fatty acyl-coenzyme As to produce various subspecies of (dihydro)ceramides...

Spotlight: pacFA Ceramide

Posted on February 21, 2018

Dr. Erhard Bieberich's laboratory at Georgia Reagents University is interested in proteins that mediate the regulation of cilia and flagella by ceramide. Flagella and cilia are sensory and motor cellular organelle responsible for moving extracellular fluids and particles and propelling cells and unicellular organisms...

Biophysical Society Meeting: February 27- March 2, 2016

Posted on February 21, 2018

On February 27- March 2, 2016, The Avanti Roadshow will be at the 60th Annual Biophysical Society Meeting in Los Angeles, CA! Year after year, the Biophysical Society Meeting is a great place that brings together some of the leading scientists from around the world. With over 7,000 attendees and 500 speakers, Avanti loves this meeting because it still maintains the “small meeting” feel. It is a great place for learning and networking.

140th Edition-The Lipid Lowdown

Posted on February 21, 2018

The proatherogenic properties of the cholesterol 5,6-secosterols (atheronal-A and atheronal-B), recently discovered in atherosclerotic arteries, have been investigated in terms of their effects on monocyte/macrophage function. A fluorescent analogue of atheronal-B, when cultured in either aqueous buffer or in media containing fetal calf serum, is rapidly taken-up into cultured macrophage cells and accumulates at perinuclear sites...

Spotlight: MVL5/GMO Delivery System for siRNA/DNA

Posted on February 21, 2018

The therapeutic promise of gene therapy in treating and altering disease states has provided significant motivation in developing improved methods to deliver genes to cells [1,2]. Currently, two major classes of gene delivery vectors exist: viral and synthetic...

Product Spotlight: Fluorescent Endocannabinoids

Posted on February 21, 2018

Avanti’s new Fluorescent Endocannabinoids may be used to map the impact of various treatments and inhibitors on endocannabinoid uptake and distribution in living cells.

The Lipid Lowdown-Potential To Treat Type II Diabetes

Posted on February 21, 2018

PAHSA levels correlate highly with insulin sensitivity and are reduced in adipose tissue and serum of insulin-resistant humans. In adipocytes, PAHSAs signal through GPR120 to enhance insulin-stimulated glucose uptake. Thus, FAHFAs are endogenous lipids with the potential to treat type 2 diabetes.

Nanomedicines Symposium: Advances in Materials, Manufacturing & Therapeutic Applications

Posted on February 21, 2018

Precision Nanosystems' engineers and scientists will be available to demonstrate the full NanoAssemblr product suite.

Lipids for Liposomes: Selection, Preparation and Application Video

Posted on February 21, 2018

Dr. Di Bush gave a presentation at CRS in Seattle, Washington. Her presentation covered the selection, preparation and application of liposomes. To see her full presentation click the link below.

NEW products this week: 9/19/2016

Posted on February 21, 2018

14:0 Sphingomyelin. This adds to the list of 19 Natural and Synthetic SM’s and derivatives currently available.

NEW products this week: 10/03/2016

Posted on February 21, 2018

This adds to the list of 13 Functionalized PEG Lipids currently available.

147th Edition of the Avanti Newsletter

Posted on February 21, 2018

Whether you are looking for phospholipids, sphingolipids, sterols, or any other of our numerous product offerings, Avanti’s research products are the highest purity lipids on the market and give you the best possibility for success.

NEW products this week: 10/17/2017

Posted on February 21, 2018

Deuterated Hydroxy Phytosphingosine (S & R), Deuterated Hydroxy Ceramide (S & R), Deuterated Hydroxy Sphinganine (S & R), Deuterated Phytosphingosine. Deuterated Hydroxy Sphingosine...

New products this week: 10/31/2016

Posted on February 21, 2018

These new derivatives gives the researcher a choice of 19 Deuterated Ceramides from which to choose CER7-2’R,6R(d9) CER7-2’S,6R(d9)

This week in research: March 29, 2017

Posted on February 21, 2018

Researchers from Northwest University (Xi’an, Shaanxi, China) used numerous lipid analytical standards from Avanti in a serum lipidomic analysis using UPLC-QTOF/HDMS to study lipid metabolism in chronic kidney disease (CKD). This interesting work identifies profound changes in lipid metabolites in individuals with CKD...

This week in research: April 5, 2017

Posted on February 21, 2018

People do Amazing Things with Our Lipids! Researchers from the National Center for Global Health and Medicine (Tokyo, Japan) are studying the role of PAF signaling in neuropathic pain, a chronic pain condition resulting from injury of the peripheral or central nervous systems. PAF, as well as, ATP and lyophosphatidic acid are thought to be central mediators of neuropathic pain.

Categories